A Rat Model of Progressive Chronic Renal Failure Produced by Microembolism
نویسندگان
چکیده
منابع مشابه
Identifying and slowing progressive chronic renal failure.
OBJECTIVE To help inform primary care physicians about how to identify and slow progressive chronic renal failure. QUALITY OF EVIDENCE The National Library of Medicine (1996 to 2000) was searched using PubMed with search terms pertinent to studies on identification, course, and management of chronic renal failure. References in retrieved papers and older literature known to the authors supple...
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Uremic toxins have been suggested to promote progression of chronic renal failure by damaging tubular cells. Previous in vitro studies have indicated that some uremic toxins induce oxidative stress and activate NF-kappaB to upregulate plasminogen activator inhibitor-1 in tubular cells. These mechanisms may promote tubulointerstitial fibrosis. The present study examined whether uremic toxins ind...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 1999
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)65239-x